Study of an injection for chronic sinusitis with nasal polyps
Part of Ear, nose & throat clinical trials.
This study tests an injection called LP-003 that may help reduce nasal polyps and improve breathing. It's for people whose symptoms are not controlled by standard treatments like steroid sprays or surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with nasal polyps in both nostrils (chronic sinusitis with nasal polyps).
- You have had a stuffy nose plus one other symptom (runny nose, facial pain/pressure, or reduced sense of smell) for at least 4 weeks.
- Your symptoms are still moderate to severe even after trying steroid pills or sprays, or you had sinus surgery in the past 6 months.
- You are willing to use a steroid nasal spray (mometasone) regularly for at least 2 weeks before starting the study.
- You have not recently used certain biologic injections (like Dupixent or Nucala) or oral steroids that could interfere with the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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