Testing BHV-7000 for inherited erythromelalgia pain
Treatments studied
Part of Brain & nervous system, Heart & circulation, Pain clinical trials.
This clinical trial tests an investigational medication (BHV-7000) for people with inherited erythromelalgia caused by a specific NaV1.7 gene mutation. The study aims to see if the drug can safely reduce the chronic burning pain that is typical of this condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have a confirmed inherited form of erythromelalgia (a rare condition causing severe burning pain in hands/feet) caused by a specific NaV1.7 gene change.
- You do not have a different genetic change (Kv7.2/7.3) that affects nerve channels.
- Your pain medicines have been stable for the last 30 days and you can keep them the same during the study.
- You can and will stick to the study schedule, including filling out daily pain diaries.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how mineralocorticoid-related hormone signaling affects small heart blood vessels and how efficiently the heart works in people with high blood pressure. It may help doctors understand which treatments could improve heart function in hypertension.
This study tests a new medicine called BHV-7000 for adults whose focal seizures (starting in one part of the brain) are not controlled by current treatments. The goal is to see if it can reduce seizures safely.
This study tests a new investigational drug called HRS-6257 in healthy volunteers. It looks at how the drug works in the body and checks for side effects after one or several doses.
This study checks the long-term safety of BHV-7000 for people who already completed an earlier trial with this drug. You keep taking the same medicine while doctors watch for any side effects over time.
This trial tests if the blood pressure drug enalapril can reduce pain from venous malformations (abnormal veins). It may help people whose pain limits daily activities or interrupts sleep.
This study tests new treatments for chronic pain that lasts at least 3 months. Participants must stop their regular pain medicines and use only a rescue painkiller if needed. The goal is to find better ways to manage long-term pain.
Hear when a new Familial Erythromelalgia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.