Test a heart and blood-pressure therapy in people with hypertension
Treatments studied
Part of Heart & circulation clinical trials.
This study looks at how mineralocorticoid-related hormone signaling affects small heart blood vessels and how efficiently the heart works in people with high blood pressure. It may help doctors understand which treatments could improve heart function in hypertension.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a history of high blood pressure
- Your recent blood pressure fits the study limits (higher if you are not on BP medicines)
- Your echocardiogram shows thick heart muscle (LVH) meeting sex-specific thickness cutoffs
- You have not used certain hormone-blocking pills in the last year (eplerenone, spironolactone, finerenone) or amiloride
- You do not have certain heart or stroke/heart-attack history or unstable heart symptoms in recent months
- Your kidney, liver, thyroid, and blood salt levels are not significantly abnormal, and you are not pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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