Clin2
NCT07267260Possibly a fitRecruiting

Vonoprazan to prevent ulcers after variceal banding

Cirrhoses, Liver

Treatments studied

Part of Digestive system clinical trials.

This trial tests whether vonoprazan can reduce ulcers caused by a procedure that ties off enlarged veins in the esophagus (variceal band ligation). It is meant for people with liver cirrhosis who are scheduled to receive this treatment.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
154 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are 18 to 75 years old
  • You have liver cirrhosis confirmed by a doctor or imaging
  • You have enlarged veins in your esophagus that need to be tied off
  • You can give permission in English or Urdu
  • You are willing to take the study medicine and attend follow-up exams

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07608536Not yet recruiting· Phase 3
Comparing two acid reducers to prevent ulcers after variceal treatment

This study compares two medications, rabeprazole and vonoprazan, to see which one works better at preventing ulcers that can form after a procedure to treat varices (enlarged veins) in the esophagus. If you have cirrhosis and varices, this trial may help reduce pain and bleeding after your treatment.

Lucknow, Uttar Pradesh
NCT07248722Enrolling by invitation
Pantoprazole after preventive variceal treatment

This trial tests whether a heartburn medication (pantoprazole) helps patients with liver cirrhosis who have had a procedure to treat enlarged veins in the esophagus or stomach. It looks at how well the medicine works when given after this procedure to prevent complications.

Shenyang, Liaoning
NCT07437768Enrolling by invitation
Vonoprazan test for acid reflux that doesn't respond to standard medicine

This trial tests a medicine called vonoprazan for people whose acid reflux symptoms (like heartburn or coughing) don't get better with usual treatment. It aims to see if vonoprazan can help control those symptoms.

New Taipei City, Taiwan
NCT06953986Recruiting
Comparing three medicines for severe acid reflux healing

This trial tests vonaprazan (two doses) against esomeprazole to see which better heals moderate-to-severe reflux esophagitis (a damaged esophagus from acid reflux) in 8 weeks. You may qualify if you have had heartburn or regurgitation for at least a month and your doctor found grade B, C, or D damage on an endoscopy.

Hyderabad, Telangana
NCT06783257Not yet recruiting· Phase 2
Study of vonoprazan injection for bleeding ulcers

This study tests an investigational medicine given as an injection to help stop bleeding from stomach or duodenal ulcers. It may offer a new option for people who have active bleeding from these ulcers.

NCT07049146Not yet recruiting
Preventing recurrent gastric variceal bleeding with two procedures

This trial tests two procedures to prevent re-bleeding from enlarged veins in the stomach (gastric varices) in people with liver cirrhosis. Both procedures aim to block off the abnormal veins to reduce the risk of another bleeding episode.

Chengdu, Sichuan

Hear when a new Cirrhoses, Liver trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.