Helping preterm babies breathe with gentle pressure during surfactant therapy
Part of Women’s health & pregnancy clinical trials.
This trial tests whether using a special chest-contouring device (cuirass) that creates gentle negative pressure around the chest can help preterm babies who need surfactant (a substance that helps lungs stay open) breathe better without a breathing tube.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby is born at 32 weeks of pregnancy or later
- Your baby needs extra oxygen (more than 30% oxygen for over 30 minutes) while on continuous positive airway pressure (CPAP) or high-flow nasal cannula
- Your baby shows signs of hard work breathing even with low oxygen needs
- Your baby weighs more than 800 grams (about 1 pound 12 ounces) at birth
- A chest X-ray shows respiratory distress syndrome (RDS)
- The hospital has all the needed equipment and a correctly sized chest cuirass for your baby
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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