Timing of Nalbuphine for Pain and Blood Pressure in Older Knee Surgery Patients
Part of Pain clinical trials.
This study tests whether giving the pain medicine nalbuphine at different times during knee replacement surgery affects blood pressure and pain control in older adults. It may help find the best timing to reduce pain and keep vital signs stable.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 65 years or older.
- You are scheduled for a total knee replacement (one knee) under general anesthesia (you will be asleep).
- Your body mass index (BMI) is between 18 and 30 (a healthy to moderately overweight range).
- You have no serious mental health conditions, can think clearly, and communicate well.
- You do not have uncontrolled high blood pressure (above 180/100 mmHg), severe lung disease, or significant liver or kidney problems.
- You do not have a history of drug abuse or heavy alcohol use (more than 2 drinks per day).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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