Y-4 for postherpes nerve pain
Treatments studied
Part of Brain & nervous system, Pain clinical trials.
This trial tests a new drug called Y-4 for people with lingering nerve pain after shingles (postherpetic neuralgia). If you have had pain for more than a month after your rash healed, this study may help find a new treatment option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Your shingles rash has healed, but you still have pain in that area for more than one month.
- Your pain in the last 24 hours was at least 40 on a 0-100 pain scale.
- You have not had nerve blocks, acupuncture, or other treatments for this pain in the past week.
- You are not pregnant and willing to use birth control during the study.
- You do not have other serious health issues like uncontrolled high blood pressure, liver or kidney problems, or a history of cancer in the past 5 years.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether adding esketamine to two standard pain medicines (pregabalin and duloxetine) can better treat nerve pain from shingles that persists for months. It's for people whose pain hasn't improved enough with pregabalin alone.
This trial tests whether the drug venlafaxine, usually used for depression, can help prevent long-term nerve pain (postherpetic neuralgia) after a shingles infection. If you are currently experiencing shingles pain, joining this study might reduce your chances of developing chronic pain later.
This trial tests a pain-relieving brain stimulation treatment for people with long-lasting pain after shingles (called postherpetic neuralgia). It compares the real treatment to a sham (inactive) procedure to see if it truly reduces pain.
This study tests a treatment called peripheral nerve stimulation (using a small device to send mild electrical pulses) for people with nerve pain after shingles. It's designed for those whose pain is not well managed by usual treatments.
This study tests whether electroacupuncture (a type of acupuncture using mild electric pulses) can reduce nerve pain after shingles. It also looks for biomarkers to see how the treatment works.
This trial tests whether adding acupuncture (electroacupuncture) to the standard pain medicine pregabalin can better relieve facial shingles pain that started 1 to 3 months ago. It's for people with moderate pain who are willing to try both treatments together.
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