Understanding vision loss in Usher syndrome type 1B
Part of Brain & nervous system, Ear, nose & throat, Eyes & vision, Genetic & congenital clinical trials.
This study follows people with Usher syndrome type 1B over time to learn how vision loss progresses. It also tests new ways to measure functional vision, which may help design future treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed diagnosis of Usher syndrome type 1 (USH1) in both eyes, with genetic changes in the MYO7A gene.
- You are at least 3 years old.
- If participating in special vision tests, you are between 18 and 75 years old and have a cochlear implant to hear instructions.
- You are enrolled in French social security or a similar system.
- You are not currently in an experimental treatment trial or have been in the previous MYO7A gene therapy trial (USHSTAT).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This 24-month study tests an experimental medication, NPI-001, to see if it can slow or prevent further vision loss in people with Usher syndrome. Usher syndrome affects hearing and vision, and this trial focuses on protecting the light-sensing cells in the retina.
This study tests a 24-month treatment with NPI-001, an oral medication, to see if it can slow the loss of light-sensing cells in the retina for people with retinitis pigmentosa tied to Usher syndrome. It aims to preserve remaining vision and delay further damage.
This study follows people with Usher syndrome over time to better understand how hearing and vision symptoms change. It may help researchers measure disease progression and support future treatments.
This trial tests an experimental gene therapy given as an injection under the retina. It aims to slow or stop vision loss in people with Usher syndrome type 1B, a rare genetic condition that causes both hearing and vision problems.
This study tests a new imaging technique to better understand and monitor a type of inherited vision loss caused by changes in the USH2A gene. It may help improve diagnosis and future treatment planning for people with this condition.
This study will check if certain vision tests work well in people with retinal diseases like retinitis pigmentosa or Stargardt. Results will help design future trials.
Hear when a new Usher Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.