Muscle loss and survival in critically ill patients on breathing machines
Part of Brain & nervous system clinical trials.
This study looks at how muscle loss in the thigh affects survival in very sick patients who need a breathing tube. If you join, the research team will use a simple ultrasound to measure your thigh muscle on day 1 and day 7.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- Your breathing is expected to be supported by a ventilator for at least 48 hours.
- Before this illness, you were not extremely frail (needing full care).
- You do not have a history of nerve or muscle disease affecting your muscles.
- You have both legs intact (no amputations) and no major thigh injuries or conditions.
- You are able to cooperate during an ultrasound examination of your thigh.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies ways to improve recovery of skeletal muscle in people who have been very sick in the ICU. It focuses on preventing problems with the body’s muscle “repair cells” after critical illness.
This study checks if a simple ultrasound test of your muscles can help doctors decide when you are ready to breathe without a breathing tube. The test is painless and may help make weaning safer.
This study looks at muscle loss and swallowing problems in very ill patients on breathing machines in the intensive care unit. It aims to understand these issues better, which could help improve care for future patients.
This study checks how leg muscles recover after being in the ICU on a breathing machine. It uses a strength test and a special ultrasound to measure muscle health.
This study looks at how frailty relates to muscle thickness in the thigh for patients over 65 who stay in the intensive care unit for at least a week. It aims to find ways to better support recovery.
This study looks at muscle function and disease severity in people who have been in the intensive care unit (ICU) for at least 48 hours. It aims to understand how muscle problems relate to recovery and risk, without requiring a breathing machine.
Hear when a new Mortality trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.