Clin2
NCT07280494Likely a fitRecruiting

CD7-targeted CAR-T for MRD after transplant

CD7+ T-ALL/LBL

Treatments studied

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This trial tests a special immune cell therapy (CAR-T) that targets CD7, a protein found on T-cell leukemia and lymphoma cells. It is for people who have very small amounts of cancer remaining after a stem cell transplant.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
18 people
Ages
3 years to 80 years
Study type
Interventional

Who can take part

  • You must be at least 3 years old and have given consent (or a guardian for you).
  • Your leukemia or lymphoma must be T-cell type and have a very small amount of leftover disease (MRD) after a stem cell transplant.
  • Your cancer cells must have a specific marker called CD7 on them.
  • Your liver, kidney, and heart function must be good enough (your doctor will check blood tests).
  • You cannot have an active infection, serious heart problems, or be pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06420076Recruiting· Phase 1/Phase 2
Sequential CAR-T therapy for CD5/CD7 positive T-cell leukemia/lymphoma

This trial tests a new type of immune cell therapy (called CAR-T) that targets two proteins, CD5 and CD7, on the surface of T-cell leukemia or lymphoma cells. It may be an option for people whose cancer came back or didn't respond to standard treatment.

Beijing, Beijing Municipality
NCT06316427Recruiting· Phase 1/Phase 2
CD7 CAR-T therapy for T-cell cancers that returned

This trial tests a new kind of immunotherapy called CD7 CAR-T therapy for people with T-cell cancers (like leukemia or lymphoma) that have come back or not responded to treatment. The CAR-T cells are made from your own immune cells or a donor's, and they are designed to find and destroy cancer cells that carry the CD7 marker.

Beijing, Beijing Municipality
NCT07143929Recruiting· Phase 1
CD7-targeted CAR-T therapy for relapsed or refractory peripheral T-cell lymphoma

This trial tests a new type of immunotherapy called CAR-T that targets a protein called CD7 on cancer cells. It is for people with peripheral T-cell lymphoma that has come back or not responded to at least one prior treatment.

Beijing
NCT07109518Recruiting· Phase 1
CD7 CAR T-Cell Therapy for Blood Cancers That Return or Don't Respond

This trial tests a new CAR T-cell therapy targeting CD7, a protein on some blood cancer cells. It is designed for patients whose T-cell leukemia/lymphoma or other CD7-positive blood cancer has not responded to standard treatments or has returned.

Tianjin, Tianjin Municipality
NCT06608732Recruiting· Phase 2
CAR-T therapy plus stem cell transplant for B-cell ALL with MRD

This trial tests a combination of a CAR-T cell therapy (Inaticabtagene Autoleucel) followed by your own stem cells being transplanted back into you. It is for teenagers and adults who have B-cell acute lymphoblastic leukemia (ALL) that is in first complete remission but still has tiny amounts of cancer cells (called MRD) that can be detected by sensitive tests.

Tianjin, Tianjin Municipality
NCT06136364Recruiting· Phase 1
CD7 CAR-T therapy for relapsed T-cell leukemia/lymphoma

This trial tests a new treatment called CD7 CAR-T, which uses your own immune cells modified to find and attack cancer cells that have a protein called CD7 on their surface. It's for people with T-cell acute lymphoblastic leukemia or T-cell lymphoblastic lymphoma that has come back or not responded to standard treatments.

Shanghai

Hear when a new CD7+ T-ALL/LBL trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.