Clinical trials
Colchicine clinical trials
Below are recruiting colchicine clinical trials, each written for real people, not researchers. We’re tracking 52 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07287345RecruitingPhase 4
Colchicine’s effect on inflammation after heart bypass surgery
This trial tests whether the drug colchicine can reduce inflammation after planned coronary artery bypass graft (CABG) surgery. It may help patients recover better by lowering inflammatory markers.
Lexington, KentuckyAges 18–99 - NCT07362966RecruitingPhase 4
Colchicine for heart health after a heart attack
This study tests whether a low-dose medicine called colchicine can reduce inflammation and slow down artery blockages in people who have a specific gene change (TET2) and have recently had a heart attack. The goal is to see if it helps prevent future heart problems.
Shenyang, LiaoningAges 40–85 - NCT07247734RecruitingPhase 2
Colchicine for insulin sensitivity in type 1 diabetes
This trial tests whether a daily oral medication called colchicine can improve how your body responds to insulin. It is for people with type 1 diabetes who have ongoing low-level inflammation and are already using a continuous glucose monitor.
Gentofte MunicipalityAges 18–80 - NCT06930885RecruitingPhase 3
Polypill and colchicine for heart and artery risk
This trial tests a combination pill (polypill) and a medicine called colchicine to see if they can lower the risk of future heart attacks, strokes, or other artery problems. It is for people who already have a history of heart or blood vessel disease.
Maceió, AlabamaAges 45 years+ - NCT06802926RecruitingPhase 4
Colchicine to prevent graft failure after bypass surgery
This study tests whether a low dose of colchicine, an anti-inflammatory drug, can help prevent the graft (new blood vessel) from failing after heart bypass surgery. It's for people who just had a bypass and are still in the hospital.
ShanghaiAges 18 years+ - NCT06352632RecruitingPhase 3
Adaptive Stroke Trial Testing New Treatments
This trial is testing different treatments for stroke patients to find which work best. It's designed to adapt over time so new treatments can be added as research progresses.
Sydney, New South WalesAges 18 years+ - NCT06215989Recruiting
Low-dose colchicine for acute coronary syndrome
This trial tests whether a low dose of the anti-inflammatory drug colchicine can help people who have recently had a heart attack or unstable angina. It aims to see if colchicine reduces the risk of future heart problems.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05873881RecruitingPhase 3
Colchicine and vitamin B1 for ischemic heart failure
This study tests whether colchicine and thiamine (vitamin B1) can improve outcomes in people with heart failure caused by blocked or narrowed heart arteries. It’s mainly for people with moderate-to-severe symptoms and reduced heart pumping ability.
Hamilton, OntarioAges 45 years+ - NCT05633810RecruitingPhase 3
Testing colchicine plus coated aspirin to prevent heart events
This Phase 3 study tests whether colchicine and a special type of aspirin can lower the risk of future heart attacks, strokes, or other major heart problems in people with type 2 diabetes who have not had a prior heart event. It aims to reduce cardiovascular risk using medicines that may calm inflammation and protect blood vessels.
Bentley, Western AustraliaAges 55–80 - NCT04774159RecruitingPhase 3
Low-dose colchicine to lower risk in leg artery disease
This trial tests whether low-dose colchicine can reduce “residual” risk—future heart and blood-vessel problems—in people with peripheral artery disease (PAD). It targets PAD symptoms and complications like poor blood flow in the legs, even after certain procedures.
New Haven, ConnecticutAges 18 years+ - NCT07762807Recruiting
Colchicine for people on dialysis
This study tests whether the medicine colchicine, which reduces inflammation, can be safely given to people having haemodialysis. It aims to see if it's possible to run a larger trial in the future.
LondonAges 18 years+ - NCT06158698RecruitingPhase 3
Colchicine for heart inflammation with arrhythmias
This trial tests whether the drug colchicine can help people with heart muscle inflammation (myocarditis) that also causes abnormal heart rhythms, a weak heart pump, or high stress markers. Colchicine is an anti-inflammatory medicine that might reduce heart damage and improve symptoms.
Naples, CampaniaAges 18 years+ - NCT05618353RecruitingPhase 4
Colchicine before surgery to lower heart and inflammation complications
This trial tests whether taking colchicine around the time of surgery can reduce bad events after surgery in people at higher heart risk. It focuses on helping prevent complications related to inflammation after an operation.
Birmingham, AlabamaAges 18 years+ - NCT07349875RecruitingPhase 4
Colchicine for non-severe coronary plaque: a trial
This trial tests if the anti-inflammatory drug colchicine can help people with non-severe coronary artery plaque seen on a CT scan. It may be an option if you have stable chest pain or related symptoms and your heart arteries are partly blocked but not severely.
NanjingAges 18 years+ - NCT07143136RecruitingEarly Phase 1
Colchicine for heart attack patients with stents
This trial tests if giving colchicine early after a heart attack (when a drug-coated stent is placed) can help reduce complications. It looks at short-term benefits for people with Non-STEMI.
Asyut, Asyut GovernorateAges 18 years+ - NCT07064109Recruiting
Colchicine for inflammation after heart attack
This trial tests if colchicine, an anti-inflammatory medicine, can help people who recently had a heart attack. It looks for markers in your blood to see who might benefit most.
ShanghaiAges 18–80 - NCT07026994RecruitingPhase 2
Colchicine to prevent another brain bleed from CAA
This trial tests if colchicine can reduce the risk of another stroke caused by bleeding in the brain due to a condition called cerebral amyloid angiopathy (CAA). You may qualify if you've recently had a brain bleed from CAA and have certain signs on brain scans.
BeijingAges 55 years+ - NCT06998862RecruitingPhase 3
Colchicine for people with chronic kidney disease
This trial tests whether colchicine, a drug that reduces inflammation, can help prevent further heart problems or strokes in people with moderate chronic kidney disease. You may be eligible if you have kidney disease and have had a heart attack, stroke, or related event in the past.
Madrid, MadridAges 18–99 - NCT06855433RecruitingPhase 2
Colchicine for CPPD: reducing pain and inflammation
This trial tests if colchicine can reduce pain and swelling in people with CPPD (calcium pyrophosphate deposition disease), a type of arthritis. If you have had a swollen, red, or warm joint in the last 3 months and your pain is moderate or higher, this study may offer a possible treatment.
Birmingham, AlabamaAges 40 years+ - NCT06578182RecruitingPhase 3
Can colchicine reduce knee or hip replacement?
This study tests whether a low-dose medicine called colchicine can lower the chance that people with knee or hip arthritis will need a joint replacement. If you have arthritis in your knee or hip and are not already scheduled for surgery, you may be able to join.
NijmegenAges 45–80 - NCT06543082RecruitingPhase 4
Study on heart attack patients with antiplatelet and colchicine therapy
This trial is for people who had a heart attack and received a specific type of stent (Orsiro). It tests a combination of a single antiplatelet drug and colchicine to see if it helps prevent future heart problems. Colchicine is a medicine that reduces inflammation and might lower the risk of another heart attack.
Seongnam-si, Gyeonggi-doAges 20–90 - NCT06440694RecruitingPhase 3
Colchicine to reduce inflammation after a first blood clot in the leg
This trial tests if colchicine, a medicine used for gout, can reduce inflammation after a first deep vein thrombosis (blood clot in a large leg vein). It might help prevent long-term leg problems from the clot.
Ottawa, OntarioAges 18 years+ - NCT06336733RecruitingPhase 3
Trial of anakinra for FMF attacks in patients who refuse daily shots
This trial tests if taking anakinra (a targeted medicine) only when you have a painful FMF attack can help, instead of taking it every day. It is for people with Familial Mediterranean Fever (FMF) whose attacks continue despite taking colchicine, and who do not want daily injections.
ParisAges 6 years+ - NCT06279000RecruitingPhase 3
Colchicine for heart risk during major non-heart surgery
This study tests whether a low-cost, anti-inflammatory drug called colchicine can reduce heart complications after major non-heart surgery. If you have heart or blood vessel risk factors and are scheduled for a major operation, this trial may help protect your heart.
Sankt Gallen, Canton of St. GallenAges 45 years+
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Common questions
- Are there clinical trials for colchicine?
- Yes. Clin2 currently lists 52 recruiting colchicine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colchicine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colchicine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.