Clin2
NCT07302126Possibly a fitNot yet recruiting

Bergmann enema to prevent radiation rectal injury

Acute Radiation Enteritis

Part of Cancer, Digestive system clinical trials.

This trial tests whether a Bergmann enema can help prevent radiation-related rectal injury during short-course radiotherapy for rectal cancer. It may be an option for people who are about to start pelvic radiation.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
40 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have been diagnosed with mid- or lower rectal cancer.
  • You are scheduled to receive a short course (5-7 treatments) of pelvic radiation over 5 days.
  • You have not had radiation to your pelvic area before.
  • You are not allergic to Bergmann enema.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07548736Not yet recruiting· Phase 2
Dexamethasone enema for radiation damage to the rectum

This trial tests whether a steroid enema (dexamethasone) can help prevent or reduce bowel damage caused by radiation therapy for rectal cancer. If you're starting or recently started radiation for rectal cancer, this may help protect your bowel health.

Guangzhou, Guangdong
NCT06776016Recruiting· Phase 2
Dietary supplement for radiation-related rectal injury

This trial tests a dietary supplement to help heal damage inside the rectum caused by pelvic radiation therapy. If you have mild to moderate rectal bleeding but no signs of cancer recurrence, you may be able to join.

Guangzhou, Guangdong
NCT07521605Not yet recruiting· Phase 2
Short-course radiation with chemotherapy and immunotherapy for rectal cancer

This trial tests a combination of brief radiation therapy, two chemotherapy drugs (nal-IRI and capecitabine), and an immunotherapy drug (camrelizumab) for locally advanced rectal cancer. The goal is to shrink the tumor and improve outcomes before surgery.

Guangzhou, Guangdong
NCT06325982Recruiting
Preventing rectal injury from radiation with a medicated enema

This trial tests whether a medicated enema can help prevent radiation damage to the rectum during pelvic radiotherapy. It may be a good option if you are starting radiation to the pelvis or rectum and are otherwise in good health.

Xiamen, Fujian
NCT06729645Not yet recruiting
Radiation therapy for elderly or frail patients with rectal cancer

This trial tests a combination of two types of radiation therapy (external beam and high-dose-rate brachytherapy) for elderly or frail patients with rectal cancer who cannot or choose not to have surgery. The goal is to see if this approach is effective and well-tolerated.

Kempten, BaBaden-Württembergs
NCT06991465Recruiting· Phase 2
Organ preservation trial for rectal cancer using shorter radiation

This trial tests a shorter course of radiation to the pelvis to treat rectal cancer, with the goal of avoiding surgery and preserving the rectum. It may be an option for people with advanced rectal cancer that has not spread to other organs.

Montreal, Quebec

Hear when a new Acute Radiation Enteritis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.