Clin2
NCT07304154Possibly a fitRecruiting

Study of KITE-363 for autoimmune nerve diseases

Chronic Inflammatory Demyelinating PolyneuropathyMyasthenia GravisMultiple Sclerosis

Treatments studied

Part of Brain & nervous system, Cancer, Immune system & allergy clinical trials.

This trial tests a new treatment called KITE-363 for people with certain autoimmune nerve diseases, such as multiple sclerosis, myasthenia gravis, or chronic inflammatory demyelinating polyneuropathy, that have not responded well to standard therapies. The goal is to see if it is safe and effective.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
52 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must have one of these conditions: multiple sclerosis (relapsing or progressive types), myasthenia gravis, or chronic inflammatory demyelinating polyneuropathy.
  • Your condition must still be active despite trying at least one or two standard treatments.
  • You must agree to use birth control if applicable.
  • You cannot have had a stem cell or organ transplant in the past.
  • You cannot have any other nerve disorder that might affect the results.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06939166Recruiting· Early Phase 1
Immune cell therapy for relapsed neurological autoimmune diseases

This trial tests a new type of immune cell therapy (CAR T-cells) that targets CD19 and BCMA proteins on B cells. It is for people with certain neurological autoimmune diseases that have come back or not responded to standard treatments. The goal is to see if this therapy can help control the disease.

Tianjin
NCT04561557Recruiting· Early Phase 1
Cell therapy for relapsing nervous system autoimmune diseases

This early-phase trial tests CT103A “CAR-T” cell therapy to treat certain relapsing or treatment-resistant autoimmune diseases that affect the nervous system. It aims to see whether the cells are safe and may help reduce disease activity when standard treatments haven’t controlled symptoms.

Wuhan, Hubei
NCT07392528Not yet recruiting· Early Phase 1
CAR T-cell therapy for relapsed neurological autoimmune diseases

This early-stage trial tests a new type of immune cell therapy (CAR T-cells) against several relapsed or hard-to-treat autoimmune diseases that affect the nervous system. The goal is to see if this treatment can safely calm the immune system and improve symptoms.

Tianjin
NCT06858579Recruiting· Phase 3
Testing DNTH103 for chronic inflammatory demyelinating polyneuropathy (CIDP)

This trial tests a new drug called DNTH103 for adults with CIDP, a condition that affects nerves and causes weakness. It aims to see if the drug can help people who are currently on treatment, have tried treatment before, or are new to treatment.

Birmingham, Alabama
NCT07477639Recruiting· Phase 1/Phase 2
Testing TRX319 for worsening multiple sclerosis

This trial tests a new treatment called TRX319 for people with progressive multiple sclerosis (MS) that has been getting worse. The study wants to see if this treatment can help slow down disability progression.

Kansas City, Kansas
NCT07756268Not yet recruiting· Phase 1/Phase 2
Cell therapy for multiple sclerosis

This trial tests a new cell therapy called SYS6020 for people with multiple sclerosis that has not improved with standard treatments. The goal is to see if it can slow or stop the disease and improve symptoms.

Wuhan, Hubei

Hear when a new Chronic Inflammatory Demyelinating Polyneuropathy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.