Comparing two antibiotics for XDR typhoid fever
Treatments studied
Part of Infections clinical trials.
This trial compares two strong antibiotics, meropenem (given through a vein) and azithromycin (taken by mouth), to see which one works better for a hard-to-treat type of typhoid fever called XDR (extensively drug-resistant) enteric fever. If you have been diagnosed with XDR typhoid fever, this study aims to find the best treatment option for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 1 and 70 years old.
- Your doctor suspects you have XDR enteric fever, or a blood test has confirmed it.
- If you are a married woman of childbearing age, you must have a negative pregnancy test before joining.
- You have never had a bad reaction (like a rash or severe allergy) to azithromycin or meropenem.
- You do not have a history of heart problems with abnormal EKG, or liver issues from past azithromycin use.
- You are not taking any other medicines that could negatively interact with meropenem or azithromycin.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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