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NCT07314294Possibly a fitRecruiting

Study of EMB-01 for advanced left-sided colorectal cancer

Metastatic Colorectal Cancer

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests a new drug, EMB-01, in people with advanced left-sided colorectal cancer that has spread or cannot be removed. It may help if standard treatments have stopped working or caused side effects.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
54 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have left-sided colorectal cancer (from the splenic flexure to the rectum) that has spread or cannot be removed.
  • You have had at least one standard treatment for advanced cancer, including chemotherapy and targeted therapy, but it stopped working or caused unacceptable side effects.
  • You have not taken TAS-102, fruquintinib, or regorafenib before.
  • You are willing to provide a tumor sample from a recent biopsy or one taken in the last 2 years.
  • You have no KRAS, NRAS, or BRAF mutations, and your tumor is not HER2 positive or have certain other gene changes.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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