Liver viability test during machine perfusion
Part of Digestive system clinical trials.
This trial tests a new way to check if a donated liver is healthy while it is kept on a machine that keeps it alive before transplant. Doctors measure a substance called FMN in the fluid that flows through the liver and in bile. This could help them know how well the liver might work after transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are getting a liver transplant from a deceased donor.
- The donated liver must be kept alive on a special machine (OrganOx metra) before transplant.
- You are not getting another organ transplant at the same time (like a heart, lung, kidney, or intestine).
- You are not having a living donor or split liver transplant.
- You are not having a repeat liver transplant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
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This study tests a new way to preserve donated livers that have extra fat (steatotic livers) using a special machine that keeps the liver healthy outside the body. If successful, it could allow more livers to be used for transplantation, helping people on the waiting list get a transplant sooner.
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This study is testing whether a quick look at small liver samples during cold machine perfusion can help doctors tell if the organ is healthy enough for transplant. If it works, this method could improve transplant success by catching problems early.
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