Perfusion-guided stroke treatment for medium artery blockages
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests a new way to treat strokes caused by blockages in medium-sized brain arteries within 24 hours of symptom onset. It uses brain imaging to select patients who might benefit from a procedure to remove the clot.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You had an ischemic stroke (clot blocking blood flow) within the last 24 hours
- Imaging shows a blockage in a medium-sized brain artery, such as the M2 or M3 segment of the middle cerebral artery
- Your stroke symptoms are moderate to severe (score of 8 or more on the NIH stroke scale)
- You were independent before the stroke (able to do daily activities without help)
- You have no bleeding in the brain or other serious conditions that would make the procedure unsafe
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a clot-busting drug called tenecteplase given directly into the brain artery for people having a moderate stroke caused by a blockage in a medium-sized blood vessel. The goal is to see if it helps improve recovery when given within 24 hours of stroke symptoms starting.
This trial studies a way to sort and treat people with a specific type of acute ischemic stroke (caused by a blockage in a large brain artery). It may help doctors choose the best next steps—either a procedure or medication—faster and more appropriately.
This trial tests whether putting a small mesh tube (stent) into a blocked artery in the back of the brain can improve recovery after a severe stroke. It is for people who have had a large stroke in this area and can be treated within 24 hours of symptoms starting.
This trial tests a procedure called endovascular therapy (a way to remove the blood clot using a catheter) for people with a severe stroke caused by a large blockage in the back of the brain. The goal is to see if this treatment can improve outcomes compared to standard care.
This study tests whether removing a clot from a medium-sized brain artery using a minimally invasive procedure (catheter) can improve recovery after a stroke. It's for people who cannot get standard clot-busting medicine and whose stroke started within the last day.
This trial tests whether giving a clot-dissolving medication directly into the brain's blood vessels during a standard procedure (mechanical thrombectomy) can improve outcomes for people with a stroke caused by a blockage in a medium-sized artery. It may be an option for patients who arrive at the hospital within 24 hours of symptom onset and have enough salvageable brain tissue.
Hear when a new Stroke Ischemic trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.