Sugar metabolism study in obese patients with and without MASLD
Part of Hormones & metabolism clinical trials.
This study looks at how the liver responds to sugar given through a vein in obese patients with and without a fatty liver condition called MASLD. It may help doctors understand why some people develop liver problems from sugar and fat.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 35 and 65 years old
- Your weight has been stable (no big changes) between your first visit and surgery
- You are willing to have small tissue samples (biopsies) taken from your liver and belly fat during a planned bariatric surgery
- For the MASLD group: you have a fatty liver diagnosis, and your blood tests show your liver and kidneys are working well enough
- For the non-MASLD group: you have a BMI of 40 or more, or a BMI of 35 or more with a weight-related health problem, and no fatty liver
- You are not taking certain diabetes medicines (metformin or SGLT2 inhibitors, insulin, GLP-1 agonists)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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