Brain stimulation for PTSD and depression
Part of Mental health clinical trials.
This study tests a non-invasive brain stimulation treatment called repeated transcranial magnetic stimulation (rTMS) to see if it can improve PTSD and depression symptoms by changing brain and nervous system function. It compares different rTMS protocols to find which is more effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with post-traumatic stress disorder (PTSD) by a psychiatrist.
- You also have major depressive disorder and symptoms are stable.
- Your PTSD symptoms are at a moderate level or higher (score of 31 or more on a standard PTSD checklist).
- You have depressive symptoms (score of 10 or more on a standard depression questionnaire).
- You are either not taking psychiatric medication, or your medication has been the same for at least 4 weeks.
- You can attend study visits and follow the study procedures.
- You do not have certain other mental health conditions like schizophrenia, bipolar disorder, or autism.
- You have not had more than 5 previous TMS sessions.
- You have not had suicidal thoughts or attempts in the past year.
- You do not have a history of seizures or epilepsy (or a family history).
- You do not have certain brain conditions or previous brain surgery.
- You do not have implanted metal or electronic devices (like pacemakers).
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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