Injectable treatment for COPD flare-ups
Part of Lungs & breathing clinical trials.
This study tests a new injectable medicine called JKN2401 to see if it can reduce COPD flare-ups and improve breathing for people with moderate-to-severe COPD. It is a phase 3 trial, which means it's a late-stage test to confirm the treatment works and is safe.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a formal COPD diagnosis from a doctor and a history of smoking or exposure to indoor air pollution from cooking or heating.
- You need to be on a stable, doctor-recommended treatment plan for COPD before joining the study.
- You must have had at least one COPD flare-up (worsening of symptoms requiring extra treatment or hospital stay) recently, as defined by the study.
- You should not have asthma or other significant breathing diseases that could confuse the study results.
- You cannot have serious uncontrolled health problems, active infections, or a history of cancer that is not fully treated, unless very low-risk.
- You must not be pregnant or breastfeeding, and you must be willing to follow study rules.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether giving a special antibiotic treatment to clear a common lung fungus (Pneumocystis jirovecii) can reduce how often COPD flare-ups happen. If you qualify, this might help you have fewer severe episodes.
This study tests whether adding the drug dupilumab to usual hospital care for a severe COPD flare-up helps patients recover better than usual care alone. It is for adults with a specific type of inflammation in their blood, and may reduce the chance of future flare-ups.
This study tests an experimental drug called JKN2403 for people with moderate to severe COPD. It aims to see if the drug can reduce flare-ups and improve breathing compared to a placebo (a dummy pill).
This trial tests a new injection called XKH001 to see if it can reduce COPD flare-ups and improve lung function. It may help people with moderate to severe COPD who have had recent flare-ups despite using standard inhaled medicines.
This trial tests an injection called RC1416 for people with moderate-to-severe COPD who still have flare-ups despite using triple inhaler therapy. It may help reduce those flare-ups and improve breathing.
This trial tests a new medicine called CM512 (given as an injection) to see if it can reduce COPD flare-ups and improve lung function. It is for people with moderate-to-severe COPD who have had recent flare-ups despite using inhalers.
Hear when a new Chronic Obstructive Pulmonary Disease (COPD) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.