Clin2
NCT07333820Possibly a fitNot yet recruiting

Study of AB-201 for advanced HER2-positive stomach cancer

Malignant Neoplasm of Stomach, Unspecified

Part of Cancer, Digestive system clinical trials.

This trial tests a new drug called AB-201 for people with advanced stomach or gastroesophageal junction cancer that has HER2 protein and has not improved with standard treatments. The goal is to see if AB-201 can shrink tumors or slow the cancer's growth, and to check its safety.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
18 people
Ages
19 years and older
Study type
Interventional

Who can take part

  • You must be at least 19 years old.
  • You must have advanced (spread or cannot be removed by surgery) HER2-positive stomach or gastroesophageal junction cancer that has not responded to or you couldn't tolerate at least two previous treatments.
  • You must have had a biopsy or surgery showing HER2 positivity within the last 3 years.
  • You must have recovered from side effects of previous treatments, with at least 3 weeks since chemotherapy, 4 weeks since radiation or major surgery, and 4 weeks since immunotherapy.
  • You must have adequate organ function (kidney, liver, blood counts) and a heart pumping ability of at least 50%.
  • You must not have untreated or active brain metastases, uncontrolled infections, or significant heart disease.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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