Clin2
NCT07344467Possibly a fitRecruiting

Melatonin vs. Pregabalin for pain and anxiety after spine surgery

OralMelatoninPregabalinPostoperative PainAnxietySpine Surgery

Treatments studied

Part of Mental health, Pain clinical trials.

This trial compares two medications—melatonin and pregabalin—to see which works better at reducing pain and anxiety after spine surgery. It aims to find a safer, effective option for recovery.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
105 people
Ages
21 years to 60 years
Study type
Interventional

Who can take part

  • You are between 21 and 60 years old.
  • You are undergoing planned (elective) spine surgery.
  • You are in generally good health (ASA I or II, meaning no serious medical conditions).
  • You have no allergy to melatonin or pregabalin.
  • You do not have heart disease, kidney disease, or liver problems.
  • You do not have a psychological condition like dementia or major depression.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07777627Recruiting
Comparing two spinal pain relievers after lumbar spine surgery

This trial compares two different medications (morphine and dexmedetomidine) given through a spinal injection to see which provides better pain relief after lumbar spine surgery. If you qualify, you will receive one of these treatments or a placebo to help manage your pain after the operation.

Tanta, El-Gharbia
NCT07000201Not yet recruiting
Comparing two pain medicines before surgery in older adults

This study compares two pain-relieving medicines, pregabalin and gabapentin, given before surgery to older adults having abdominal or pelvic surgery. The goal is to see which one works better and is safer for managing pain in this age group.

Cairo, Giza Governorate
NCT07637968Not yet recruiting· Phase 4
Comparing two pain medicines after laparoscopic abdominal surgery

This study compares two pain-relieving medicines to see which works better and helps your stomach recover faster after major laparoscopic surgery. You will receive one of the two medicines during and after your operation.

NCT07670052Not yet recruiting· Phase 4
Comparing two pain medicines for gallbladder removal surgery

This study tests two different pain medicines added to the numbing medication during gallbladder removal surgery, to see which one provides better pain relief after the operation. If you're having this surgery, the study might help you have less pain afterwards.

NCT05150795Recruiting· Early Phase 1
Testing pregabalin before surgery versus fentanyl during surgery

This trial compares two medicines used around the time of surgery—pregabalin given by mouth before surgery versus fentanyl given during surgery—to see which better controls pain after the operation. You might join if you’re a generally healthy surgical patient and aren’t using certain related medicines.

Cairo
NCT07198412Recruiting
Study on sedation's effect on back pain after spinal anesthesia

This study looks at whether giving sedation (medicine to help you relax) during spinal anesthesia can reduce back pain after surgery. It's for people having certain types of surgery on their lower abdomen or legs.

Banhā, Qalyubia Governorate

Hear when a new Melatonin trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.