Short-term high-dose statin therapy after stroke
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether starting a high dose of a statin (a cholesterol-lowering medicine) soon after a stroke can improve your cholesterol levels. It is for people who have had a stroke or have significant narrowing of arteries in the brain or neck.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You had a stroke within the last 14 days, or you have a narrowing of at least 50% in a brain or neck artery.
- You are able to start a high-dose statin (like atorvastatin 40-80 mg or rosuvastatin 20 mg) within 24 hours of being admitted to the hospital.
- You are willing to take the statin for at least one week.
- You have not taken a statin in the week before your hospital stay.
- You are not pregnant or breastfeeding, and you are not on other cholesterol-lowering treatments.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two treatments for people who recently had a stroke or TIA and have high cholesterol with artery plaque. Some participants will get a combination of two cholesterol-lowering medicines (statin and ezetimibe), while others will get only a statin.
This study tests whether starting a statin soon after a stroke or mini-stroke helps older adults (70+) who are frail. You will be randomly assigned to receive a statin or a placebo to see if it reduces the chance of another stroke.
This study tests if combining the blood thinner clopidogrel with either atorvastatin or rosuvastatin (both cholesterol-lowering drugs) works better for people who have had a mild first-time stroke in the small blood vessels of the brain. The goal is to find a safe and effective treatment regimen.
This trial is testing the best target for 'bad' cholesterol (LDL) after a type of stroke caused by a small blocked vessel. You would be in one of two groups to see which LDL level helps prevent another stroke the most.
This study tests whether adding clopidogrel (a blood thinner) to atorvastatin or rosuvastatin (cholesterol-lowering drugs) helps people who had a first-time large-vessel ischemic stroke. It aims to find the best way to prevent another stroke.
This study looks at how well statins work in older stroke or TIA patients who are already taking them and also have some frailty. The goal is to understand if continuing statins is safe and helpful for this group.
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