Gene therapy study for high-grade glioma
Part of Cancer clinical trials.
This trial tests a new gene therapy given directly into the brain tumor. It's for people with high-grade glioma, either newly diagnosed or after one recurrence, to see if it can help control the tumor.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old and have a high-grade glioma (a type of aggressive brain tumor).
- You can still take care of most daily activities (Karnofsky score of 70 or higher).
- If you are newly diagnosed, you haven't had any other treatments for your brain tumor yet, and you're a candidate for standard chemoradiation therapy followed by temozolomide.
- If your tumor has come back, you've only had one recurrence after previous treatment with surgery, radiation, and chemotherapy.
- You are able to take pills by mouth, agree to use effective birth control (if applicable), and avoid live vaccines during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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