Finding the right dose of a new IV painkiller after bone surgery
Part of Pain clinical trials.
This trial tests a single dose of a new pain medicine called tegileridine fumarate given through a vein right after orthopedic surgery (like spine, hip, or knee surgery). The goal is to find the best dose that works well for pain without causing side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You are scheduled for spine surgery, hip or thigh bone surgery, or a knee replacement.
- Your overall health is rated as good to fair (ASA I–III).
- You do not have a history of chronic pain or long-term opioid use.
- You are not severely overweight (BMI 30 or less).
- You have no serious kidney or liver problems, and no severe breathing issues.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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