Orelabrutinib for untreated marginal zone lymphoma
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests a new targeted drug (orelabrutinib) with or without another drug that targets CD20 (a protein on some immune cells) for people with untreated marginal zone lymphoma. It aims to see if this combination works better than other treatments and may be an option for those who cannot have radiation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with marginal zone lymphoma (a slow-growing type of lymphoma).
- You have a tumor that can be measured on scans.
- You need treatment now because of symptoms or because your doctor says it's time.
- You are not able to get or have already tried radiation therapy for your lymphoma.
- You do not have another active cancer or lymphoma that has spread to your brain.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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