NAC vs ALA for pain after appendix surgery
Treatments studied
Part of Brain & nervous system, Pain clinical trials.
This trial tests whether adding N-acetylcysteine (NAC) or alpha-lipoic acid (ALA) to standard pain relief helps reduce pain after laparoscopic appendix removal. If you qualify, you may receive one of these antioxidants along with your usual pain medicines.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 65 years old.
- You must be scheduled for a laparoscopic (keyhole) appendix removal.
- You cannot be pregnant or breastfeeding.
- You must not have long-term pain or use strong painkillers regularly.
- You must not have serious liver or kidney problems or allergies to the study drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether injecting a local anesthetic (numbing medicine) and a steroid around the surgical area before surgery reduces pain after laparoscopic procedures like gallbladder, appendix, or hernia repair. The goal is to help patients recover more comfortably with potentially less pain medication needed.
This trial tests if a medicine called N-acetylcysteine (NAC) can reduce the need for strong pain pills after hysterectomy surgery. If you are having a laparoscopic or robotic hysterectomy, this study may help you recover with less opioid pain medicine.
This trial tests whether taking N-acetylcysteine (NAC), an antioxidant supplement, before and after surgery can help reduce long-term pain. If you're having a planned outpatient hand, arm, foot, or ankle surgery, you may be eligible.
This trial tests whether acetaminophen (a common pain reliever) works better than a placebo (a sugar pill) for pain after abdominal surgery. If you join, you will receive either the study drug or a placebo to help understand the best way to manage pain.
This trial tests if lowering oxidative stress (damage from natural body processes) during knee replacement surgery can prevent chronic pain afterward. It may help people with osteoarthritis who have moderate to severe pain before surgery.
This study compares two different nerve-blocking techniques to help manage pain after laparoscopic gallbladder surgery. Both methods use ultrasound guidance to deliver numbing medication near nerves, and the trial tests which approach works better for pain relief and overall recovery.
Hear when a new Laparoscopic Appendectomy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.