Reducing stress to prevent long-term pain after knee replacement
Part of Bones, joints & muscles, Pain clinical trials.
This trial tests if lowering oxidative stress (damage from natural body processes) during knee replacement surgery can prevent chronic pain afterward. It may help people with osteoarthritis who have moderate to severe pain before surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 50 years old or older
- You are having a first-time total knee replacement on one knee
- You have been diagnosed with osteoarthritis in that knee
- Your worst pain in the past day was at least a 4 on a 0–10 scale
- You are able to read and understand English questionnaires
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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