LM-108 with Toripalimab vs Paclitaxel for advanced stomach cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a new combination of two immunotherapy drugs (LM-108 and Toripalimab) against a standard chemotherapy drug (Paclitaxel) for people with advanced stomach or gastroesophageal junction cancer that has a specific marker called CCR8. It may be an option if you have already tried a first-line therapy and your cancer has progressed or you had side effects from chemotherapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old.
- You have advanced stomach or gastroesophageal junction cancer that cannot be removed by surgery or radiotherapy.
- Your cancer is positive for the CCR8 marker (confirmed by a central lab).
- Your cancer is HER2-negative or low-expressing.
- You have had prior treatment and your cancer worsened during or after that treatment, or you could not tolerate the side effects from chemotherapy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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