Hepatic artery infusion + immunotherapy for advanced bile duct cancer
Treatments studied
Part of Cancer clinical trials.
This trial tests combining a liver-directed chemotherapy infusion (HAIC) with immunotherapy to shrink advanced bile duct cancer that cannot be removed surgically. The goal is to slow tumor growth and improve survival.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You have advanced bile duct cancer that cannot be removed by surgery and has not been treated with systemic therapy before.
- You have at least one tumor that can be measured on scans.
- You are in good general health (able to do most daily activities).
- Your liver function is adequate (Child-Pugh class A or B).
- Your expected survival is at least 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a combination of a targeted drug (lenvatinib), an immunotherapy (PD-1 inhibitor), and chemotherapy given directly into the liver's blood supply for people with advanced intrahepatic cholangiocarcinoma (a type of bile duct cancer that starts in the liver). The goal is to see if this combination can shrink tumors or slow the cancer's growth.
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