High-dose vitamin D for low vitamin D in aggressive lymphoma
Part of Blood & lymphatic, Cancer, Hormones & metabolism, Immune system & allergy clinical trials.
This study compares a high dose of vitamin D2 (ergocalciferol) to the standard dose to see which is better at raising vitamin D levels in people with aggressive non-Hodgkin lymphoma. If you are starting your first treatment for a fast-growing lymphoma and have low vitamin D, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 20 years or older.
- You have been newly diagnosed with a fast-growing type of non-Hodgkin lymphoma (aggressive NHL) and are about to start your first treatment with chemotherapy and immunotherapy.
- Your vitamin D level is low (less than 30 ng/mL) and you haven't been taking vitamin D supplements before this study.
- You are generally able to carry out daily activities (ECOG performance status 0-3) and your organs are working well enough for standard chemotherapy.
- You do not have certain health problems, like high calcium or phosphate levels, kidney disease (stage 4 or worse), or a history of kidney stones from high calcium in urine.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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