Active surveillance for Bethesda IV thyroid nodules
Part of Cancer, Hormones & metabolism clinical trials.
This study is testing whether it is safe to simply monitor (watch closely) a small thyroid nodule that has a certain biopsy result (Bethesda IV) instead of removing it right away. You would not receive a treatment, but would have regular checkups and ultrasounds to see if the nodule changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 30 years old or older.
- You have a single thyroid nodule that a biopsy found to be a 'follicular neoplasm' or 'suspicious for follicular neoplasm' (Bethesda category IV).
- The nodule is smaller than 2 centimeters (about 0.8 inches) in every direction.
- Your thyroid ultrasound shows the nodule is low or intermediate risk (EU-TIRADS 3 or 4).
- You do not have signs that the nodule may have spread (such as suspicious lymph nodes, irregular shape, or growth outside the thyroid).
- You have not had thyroid surgery before, do not have high calcium, are not pregnant, and can give consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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