Thyroid hormone treatment in active surveillance for small thyroid cancer
Part of Cancer, Hormones & metabolism clinical trials.
This study tests whether taking thyroid hormone to lower TSH (a hormone that can stimulate thyroid cancer) is necessary for people with very small, low-risk thyroid cancers who choose active surveillance (monitoring instead of immediate surgery). It aims to find out if skipping this treatment is safe and helps avoid side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a small thyroid nodule (1 cm or smaller) that a biopsy shows is either suspicious for or confirmed as papillary thyroid cancer, or has the BRAF V600E gene change.
- The cancer has not spread to distant parts, neck lymph nodes, or nearby tissues like the voice box or windpipe.
- The tumor is not a high-risk type of papillary thyroid cancer (like diffuse sclerosing, columnar cell, or solid subtypes).
- You are not pregnant (if you are of childbearing age).
- You do not have hyperthyroidism (overactive thyroid).
- You have not had a heart attack or stroke in the last 3 months, and you are expected to be able to follow up for at least 5 years.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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