Clin2
NCT07380373Possibly a fitEnrolling by invitation

Testing markers in body fluids for lung injury in children

ARDS (Acute Respiratory Distress Syndrome)

Part of Lungs & breathing clinical trials.

This study looks at two substances in saliva and lung fluid—called IL-6 and TNF-α—in children with severe lung failure (ARDS) who are on a breathing machine. Measuring these markers may help doctors better understand the condition and guide treatment.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
37 people
Ages
1 year to 10 years
Study type
Observational

Who can take part

  • Your child must be diagnosed with acute respiratory distress syndrome (ARDS), a serious lung condition.
  • Your child must be between 1 month and 18 years old.
  • Your child must need a breathing machine (ventilator) to help them breathe.
  • We need to collect samples of saliva and fluid from the lungs (called BAL) within 24 hours of diagnosis.
  • A parent or legal guardian must sign a consent form.
  • Your child cannot have long-term lung disease, a weak immune system, active cancer, or severe birth defects that make survival unlikely.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07281911Not yet recruiting
Early lung fluid study in sepsis-related breathing failure

This study looks at the early changes in the lungs of people with sepsis who develop a severe breathing problem called ARDS. Researchers will collect small samples of lung fluid to better understand the condition and potentially improve future treatments.

Barcelona, Barcelona
NCT07633366Recruiting
Understanding ARDS Through Lung Fluid and Imaging Analysis

This study examines lung fluid samples and imaging scans from patients on breathing machines to better understand acute respiratory distress syndrome (ARDS), a serious lung condition. Researchers hope this will help doctors diagnose and treat ARDS more effectively in the future.

Vienna, State of Vienna
NCT06001645Recruiting
Lung biomarkers and air leaks in severe lung injury

This study looks for markers in the blood and signs of air trapped in the lung tissue of people with acute respiratory distress syndrome (ARDS). It uses CT scans to understand why air leaks happen and if certain lab tests can predict them.

Cagliari
NCT06164639Enrolling by invitation
Biomarkers and causes of lung injury from reflux

This study looks at why some people on breathing tubes develop lung damage from stomach acid getting into the lungs. It may help find better ways to prevent or treat this injury.

Shanghai
NCT06123962Recruiting
Identifying lung injury subtypes to guide treatment

This study looks at different patterns in patients with a severe lung condition called ARDS, to better understand why some respond to treatments differently. You may help doctors learn how to personalize care.

Beijing
NCT06746077Enrolling by invitation
Lung disease study in children: new ways to understand infections

This study explores how the immune system and lung microbes affect children with lung disease. It uses extra fluid collected during a standard lung exam to look for new treatment targets.

Aarhus N

Hear when a new ARDS (Acute Respiratory Distress Syndrome) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.