Steroid combination for septic shock
Treatments studied
Part of Infections clinical trials.
This trial tests whether two medicines (hydrocortisone and fludrocortisone) can help people with severe infections that cause dangerously low blood pressure (septic shock). It's for patients who have just been diagnosed and haven't used steroids recently.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 90 years old.
- You must have been diagnosed with septic shock within the last 12 hours.
- You cannot have taken any steroid medications in the past 3 months.
- You cannot be pregnant.
- You cannot have a known allergy to hydrocortisone or fludrocortisone.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This study tests whether giving a special combination of hydrocortisone, vitamin C, and vitamin B1 helps older adults with sepsis recover better. It looks at how the treatment affects tiny blood vessels and overall survival.
This study tests whether adding a steroid called fludrocortisone to standard care helps people with septic shock (a dangerous drop in blood pressure from infection) get better faster. If you are in the ICU, on a breathing machine, and need strong medication for your blood pressure, you may be eligible.
This Phase 3 trial tests whether giving stress-dose hydrocortisone can improve outcomes for children with septic shock in the pediatric intensive care unit (PICU). It is designed for children who are already receiving strong medicines to support blood pressure because of a serious infection.
This trial tests whether a blood filtering treatment called hemoadsorption can help protect blood vessels in people with septic shock. It may be an option for patients who are already on strong blood pressure medications and steroids.
This trial tests different combinations of blood pressure medicines given to patients on a breathing machine who have septic shock. The goal is to find the best dose of a second medicine when norepinephrine alone isn't enough.
This trial examines how the renin-angiotensin-aldosterone system (a hormone system that helps control blood pressure) changes in patients with septic shock, compared to those with sepsis without shock, cardiogenic shock, and healthy volunteers. The goal is to better understand these changes and possibly improve treatment.
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