Paxalisib for newly diagnosed glioblastoma after standard treatment
Treatments studied
Part of Cancer clinical trials.
This trial tests a drug called paxalisib in people with a newly diagnosed aggressive brain tumor (glioblastoma) who have just finished standard radiation and chemotherapy. The goal is to see if adding paxalisib can help prevent the tumor from coming back by targeting a specific pathway in the cancer cells.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a type of brain tumor called glioblastoma (IDH-wildtype, Grade 4).
- You must have finished standard radiation and chemotherapy (Stupp protocol) within the last 6 weeks, and your tumor must not have grown after that treatment.
- You must be 16 years old or older.
- You must be able to take care of yourself (fully active or able to do light work).
- Your blood counts and organ function (kidney, liver, etc.) must be within certain ranges, and you must not have uncontrolled diabetes, heart problems, or other serious medical conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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