A safer heart surgery for infants using a clear fluid prime
Part of Genetic & congenital, Heart & circulation clinical trials.
This trial tests whether using a clear fluid to prime the heart-lung machine before surgery reduces inflammation in infants weighing 5-10 kg (about 11-22 pounds). The clear fluid replaces the usual blood-based prime, possibly leading to a smoother recovery after heart surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby must weigh between 5 and 10 kilograms (about 11 to 22 pounds).
- Your baby must be between 1 and 18 months old.
- Your baby must be scheduled for heart surgery that uses a heart-lung machine (cardiopulmonary bypass).
- The surgery is planned to be performed by Dr. Bohuta or Dr. Greene.
- Your baby's blood counts must be high enough to safely use the clear prime (the care team will check this).
- Your baby must not have a genetic syndrome, must not be on ECMO (a type of life support), and must not have an active infection or a pork allergy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two ways of removing extra fluid from the body during heart surgery with a heart-lung machine in children under 5. The goal is to find which method is safer and works better.
This trial studies patterns in immune cells (neutrophils) in very young children who undergo heart surgery using a heart-lung machine. The goal is to better understand and potentially reduce lung injury after surgery.
This trial tests new surgical strategies for newborns with certain complex heart conditions. It aims to see which techniques lead to better recovery and quality of life in the first year after surgery.
This trial compares an early procedure to close a heart vessel called the ductus arteriosus versus careful observation alone in very low-birth-weight preterm infants. It aims to see whether closing the vessel early can improve outcomes and be done safely.
This trial tests if giving milrinone before surgery to close a common heart vessel (PDA) can prevent heart issues in premature babies. It may help very premature infants who need surgery for a large PDA.
This trial studies the best way to manage blood thinning (anticoagulation) during heart surgery that uses a heart-lung machine in people with obesity. It may help reduce blood-clotting and bleeding complications by comparing different care strategies.
Hear when a new Ventricular Septal Defect trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.