Heparin and bypass blood management for obese heart surgery
Treatments studied
Part of Hormones & metabolism clinical trials.
This trial studies the best way to manage blood thinning (anticoagulation) during heart surgery that uses a heart-lung machine in people with obesity. It may help reduce blood-clotting and bleeding complications by comparing different care strategies.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older
- Your body mass index (BMI) is 30 or higher
- You are scheduled for heart surgery that uses a heart-lung machine (cardiopulmonary bypass)
- You can have blood products if needed (no refusal)
- You do not have a condition that makes you unable to use heparin, such as heparin-induced low platelets
- You do not have recent or severe bleeding risk conditions like very low platelets or certain genetic clotting/bleeding disorders
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two different schedules of bemiparin (a blood thinner) to prevent dangerous blood clots after surgery in people with very high body weight. It may help find the safest and most effective dose/timing for clot prevention around the time of surgery.
This trial compares different strategies for keeping a specific blood pressure level during heart-lung bypass surgery. It may help reduce complications by finding the safest blood pressure target during the operation.
This trial tests whether collecting and re-infusing your own blood during heart surgery reduces the need for donor blood transfusions. It's for adults having planned bypass surgery with a heart-lung machine.
This study tests a blood-derived medicine (antithrombin) to help people who do not respond well to the blood thinner heparin during heart surgery. It aims to make surgery safer by improving blood thinning.
This trial tests whether using a blood thinner in people with new, temporary atrial fibrillation after CABG (heart bypass surgery) can reduce harmful outcomes compared with standard treatment. It may help prevent stroke or other complications if your rhythm problem fits the trial’s timing and risk profile.
This trial tests a medicine called 4F-PCC to stop bleeding during complex heart surgery that uses a heart-lung machine. It could help people who have bleeding problems after the surgery.
Hear when a new Cardiopulmonary Bypass trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.