CRP drug combo for older adults with untreated double-positive DLBCL
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests a new combination of drugs (CRP regimen) for older patients who have not yet been treated for a specific type of DLBCL called double-expressor lymphoma. It aims to see if this combination is effective and safe for people who may not be able to get standard chemotherapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 70 years or older, OR you are 60-69 with a health score of 2-4 on a standard scale (limited daily activity).
- You have been diagnosed with diffuse large B-cell lymphoma (DLBCL) that is CD20-positive and also has both C-MYC and Bcl-2 turned on (double-expressor).
- You have not had any previous treatment for this lymphoma, like chemo, targeted therapy, immunotherapy, or surgery (except a small biopsy).
- You have at least one tumor that can be seen on a PET-CT scan.
- Your blood counts and liver/kidney function are within a certain range (your doctor can check these).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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