Chemoimmunotherapy before surgery for head and neck cancer
Treatments studied
Part of Cancer, Ear, nose & throat, Lungs & breathing, Mouth & dental clinical trials.
This trial tests giving a combination of chemotherapy and immunotherapy before surgery for head and neck cancer. The goal is to see if this approach can shrink the tumor and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of head and neck cancer (squamous cell carcinoma) in the mouth or voice box.
- Your cancer is stage III or IVA, meaning it is locally advanced but has not spread to distant parts of the body.
- Your doctor has determined that the tumor can be removed with surgery.
- You are between 18 and 75 years old.
- You have not had any prior cancer treatment for this diagnosis.
- You have a tumor sample available for testing a marker called PD-L1.
- You have not had other cancers in the past, except for basal cell skin cancer or cervical carcinoma in situ.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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