Clin2
NCT07403266Possibly a fitRecruiting

Full-spectrum cannabis oil for seizures in tuberous sclerosis

Tuberous Sclerosis Complex (TSC)

Part of Brain & nervous system, Cancer, Genetic & congenital clinical trials.

This trial tests a full-spectrum cannabis extract to see if it reduces seizures in people with tuberous sclerosis complex (TSC) whose seizures have not been controlled by other treatments. If it works, it could offer a new option for managing hard-to-treat epilepsy.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
84 people
Ages
2 years to 65 years
Study type
Interventional

Who can take part

  • You are between 2 and 65 years old
  • You have tuberous sclerosis complex (TSC) confirmed by a doctor or genetic test
  • You have had at least 4 observable seizures in the 4 weeks before starting the trial
  • Your seizure medicines or any special diet have been stable for at least 4 weeks before starting
  • You are currently taking 3 or fewer seizure medicines (clobazam doesn't count)
  • You or your caregiver is willing to keep a daily seizure diary

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07287202Recruiting· Phase 1/Phase 2
A study of SVG103 for people with certain brain conditions and seizures

This trial tests a drug called SVG103 (Paxalisib) in adults with brain conditions that cause hard-to-control seizures: Focal Cortical Dysplasia Type II, Tuberous Sclerosis Complex, or Hemimegalencephaly. The goal is to see if SVG103 is safe and helps reduce seizures.

Heidelberg, Victoria
NCT07680322Not yet recruiting· Phase 2
AV078 for Epilepsy in Tuberous Sclerosis Complex

This trial tests an investigational drug called AV078 for people with Tuberous Sclerosis Complex (TSC) whose seizures have not been controlled by other medications. The goal is to see if AV078 can help reduce seizures safely.

NCT05534672Recruiting· Phase 3
Rapamycin for drug-resistant seizures in tuberous sclerosis

This trial tests whether rapamycin (compared with a placebo) can reduce seizures caused by tuberous sclerosis complex (TSC) that have not been controlled by usual medicines. If you qualify, you may be helping doctors find a safer and more effective option for seizure control.

Lodz
NCT07668856Recruiting· Phase 3
CBD for children with hard-to-treat epilepsy

This trial tests if adding cannabidiol (CBD) to your child's current seizure medicines can reduce seizures. It uses a personalized approach to see if CBD works for each child.

Utrecht, Utrecht
NCT05104983Recruiting· Phase 2
Sirolimus to prevent first seizures in babies with TSC

This Phase 2 study tests whether sirolimus (a targeted medicine) can stop or slow the start of seizures in very young babies diagnosed with tuberous sclerosis complex (TSC). If seizures are prevented early, it may also help protect early brain development.

Birmingham, Alabama
NCT07023744Not yet recruiting· Phase 2
Cannabinoids for drug-resistant epilepsy in adults and children

This trial tests if cannabinoids can help people who still have seizures despite trying two or more standard seizure medications. It aims to reduce seizure frequency in those with drug-resistant epilepsy.

Hear when a new Tuberous Sclerosis Complex (TSC) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.