Tracking thinking changes after CAR-T cell therapy

This study uses blood tests and brain imaging to better understand and predict nerve-system side effects that can happen after CAR T-cell treatment. It may help doctors spot people at higher risk sooner and guide safer care.

This study is for people getting CAR-T cell therapy, a type of cancer treatment that uses your own immune cells. Researchers want to understand a rare side effect called neurotoxicity by looking at tiny particles in your blood called extracellular vesicles.

This study tests if checking your pupil size with a small light device can predict brain-related side effects from CAR-T cell therapy. It is for patients with certain lymphomas receiving axi-cel CAR-T treatment in the hospital.

This trial looks at how CAR-T treatment affects the brain and thinking skills. It aims to better understand and help with side effects like confusion or memory problems.

This study looks at how a special type of immunotherapy called CAR-T therapy might affect your thinking skills, memory, and ability to focus. By checking on patients early and often, the team hopes to find simple ways to detect and manage these side effects sooner.

This study looks at how well CAR-T cell therapy works and how safely it can be given to older adults. It is for people whose cancer or related blood condition has come back or did not respond, and who are receiving a standard (commercial) CAR-T product.