Dengue infection study in healthy adults
Part of Infections clinical trials.
This trial tests how the dengue virus affects healthy adults who have never been exposed to dengue or similar viruses. You would be given a controlled dose of the virus and closely monitored to help researchers understand the infection and develop better treatments or vaccines.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 21 and 45 years old.
- You have never had dengue, Zika, yellow fever, or Japanese encephalitis, and have never been vaccinated against them.
- You are in good general health with no serious medical conditions (like heart, lung, liver, or kidney disease, or severe depression/anxiety).
- You are willing to use birth control during the study and for at least 1 month after the viral challenge.
- You have not received any vaccines 30–60 days before the study, and no experimental drugs or specific medications in the last 3–6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a controlled dengue infection in people who already have immunity to some types of dengue. It aims to understand how the immune system responds and to help develop better vaccines. You may qualify if you are a healthy adult aged 18-40 and have evidence of prior dengue exposure to certain virus types.
This study tests how the body responds to a mild, lab-made dengue virus in people who have had dengue before. It looks at how the immune system reacts to a second infection, which may help improve future vaccines and treatments.
This trial tests a new dengue vaccine in adults aged 40 to 79 to see if it can protect them from dengue fever. If you are generally healthy and willing to follow the study schedule, you may be able to join.
This trial tests a new experimental drug, EYU688, for adults with dengue fever. It aims to see if the drug is safe and effective. You may qualify if you have early dengue symptoms, have tested positive for dengue, and are otherwise healthy.
This trial tests different experimental drugs to treat dengue early. It aims to find which treatment works best and is safe for patients who start within 48 hours of fever.
This study looks at how the immune system responds to dengue fever and sepsis (a severe infection). It aims to better understand these illnesses, which could lead to improved treatments. If you have dengue-like symptoms, sepsis, or are a healthy volunteer, you may be able to join.
Hear when a new Dengue trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.