Gene therapy trial for Parkinson's with GBA1 mutation
Part of Brain & nervous system clinical trials.
This trial tests a gene therapy product called VGN-R08b for people with Parkinson's disease who have a specific genetic change (GBA1 mutation). The goal is to help improve movement and daily function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 30 to 70 years old.
- You have Parkinson's disease caused by a specific change in the GBA1 gene.
- Your GBA enzyme activity is lower than normal.
- You are able to walk without a wheelchair, though you may use a walker or cane.
- Your Parkinson's symptoms are not fully controlled by your current medications, with at least 2.5 hours of 'off' time each day.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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