Study of RENATUS® valve for severe aortic stenosis
Part of Heart & circulation clinical trials.
This study tests a new device called the RENATUS® Transcatheter Aortic Valve System for people with severe aortic stenosis. It is designed to replace the narrowed valve without open-heart surgery, and aims to see if it is safe and effective for patients with various surgical risk levels.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have severe narrowing of the aortic valve (aortic stenosis) that causes symptoms like chest pain, shortness of breath, or fainting.
- Your doctor must decide you are a candidate for a minimally invasive valve replacement called TAVR, regardless of your surgical risk.
- You must be willing to sign a consent form and follow all study procedures and follow-up visits.
- You cannot have a life expectancy of less than one year, or have had a heart attack or heart surgery in the past month.
- You cannot have untreated coronary artery disease, severe heart muscle problems, or certain blood disorders that increase bleeding risk.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new valve device placed through a small tube (catheter) to treat severe aortic stenosis, a condition where the aortic valve is narrowed and doesn't open fully. It's for patients who cannot have traditional open-heart surgery.
This study checks whether an “investigational” transcatheter aortic valve is safe and works well for people with severe, calcified aortic stenosis (a stiff, narrowed heart valve). It may help improve valve function and symptoms, but you must meet specific heart, scan, and health-status requirements.
This trial tests a new heart valve called DurAVR for people with severe aortic stenosis (a narrowed aortic valve) who need a valve replacement. It compares the new valve to standard valves to see if it is safe and works well.
This study is testing the Navitor valve, a device to replace a narrowed aortic heart valve without open-heart surgery. It will track how well the valve works in people who are already good candidates for this procedure.
This trial studies whether a new through-the-blood-vessel heart valve (TAVR) is safe and works well for people with severe aortic stenosis who are too risky for traditional surgery. If you qualify, you would be closely followed to check your symptoms and valve function over time.
This study looks at how safe and effective an emergency heart valve replacement is for people with severe aortic stenosis who are in critical condition. It may help if you have severe symptoms like shock or unstable chest pain that need urgent treatment.
Hear when a new Severe Aortic Stenosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.