Better MRI contrast for detecting cancer spread to brain lining
Treatments studied
Part of Brain & nervous system, Cancer clinical trials.
This study is testing different ways to give MRI contrast dye to better see if cancer has spread to the lining of the brain (leptomeningeal disease). It's for people with solid tumors who have had unclear results on standard scans or who are at high risk but have negative tests.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a solid tumor (like lung, breast, or melanoma) that has been confirmed by a biopsy.
- Your brain MRI was not clear for leptomeningeal disease (cancer spread to the lining of the brain) or you are at high risk but have had a negative MRI and spinal tap.
- You are 18 years old or older.
- You do not have a confirmed diagnosis of leptomeningeal disease from a spinal tap or MRI.
- You do not have any implanted devices that are unsafe for MRI (like some pacemakers or aneurysm clips).
- You are not pregnant or potentially pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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