Clin2
NCT07416994Possibly a fitRecruiting

Study of YL202 vs. docetaxel for advanced EGFR-mutant lung cancer

Non-Small Cell Lung Cancer

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a new drug, YL202, against a standard chemotherapy (docetaxel) for people with a specific type of advanced non-small cell lung cancer that has an EGFR mutation. The goal is to see if YL202 works better for those whose cancer has progressed after prior treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
440 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must be between 18 and 75 years old.
  • You must have advanced non-squamous non-small cell lung cancer with a specific EGFR mutation (Exon 19 deletion or Exon 21 L858R).
  • You must have already had one type of targeted therapy (an EGFR TKI) and one type of platinum-based chemotherapy.
  • You must be able to carry out daily activities with little help (ECOG score 0 or 1).
  • You must have at least one tumor that can be measured and has not been treated with radiation.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07070440Recruiting· Phase 1/Phase 2
DZD6008 combination therapy for EGFR-mutated lung cancer

This trial tests a new combination treatment for people with advanced non-small cell lung cancer that has an EGFR mutation. It aims to see if this combination can shrink tumors or slow their growth.

Shanghai, Shanghai Municipality
NCT07202364Recruiting· Phase 2
Study of YL202 for advanced solid tumors

This trial tests a new drug called YL202 for people with advanced solid tumors (like lung, colon, or cervical cancer) who have already tried 1-2 standard treatments. It aims to see if YL202 can shrink tumors or slow their growth.

Changsha, Hunan
NCT07169994Recruiting· Phase 1/Phase 2
Testing YL202 with other cancer treatments for advanced solid tumors

This trial is testing a new drug called YL202 in combination with other anti-cancer treatments for people with advanced solid tumors that have not responded to standard therapy. The goal is to see if this combination can shrink tumors or slow their growth.

Hefei, Anhui
NCT07442565Not yet recruiting· Phase 3
New drug versus standard chemo for advanced lung cancer

This trial compares a new drug called SYS6010 to a standard chemotherapy drug (docetaxel) for people with advanced non-small cell lung cancer that has not responded to previous treatments. The goal is to see if the new drug works better or has fewer side effects.

NCT06295432Recruiting· Phase 2
Study of two targeted drugs for EGFR-mutated lung cancer

This trial tests a combination of two targeted drugs (DZD9008 and AZD4205) for people with advanced non-small cell lung cancer that has a specific EGFR mutation and has stopped responding to standard treatments. The goal is to see if this combination can shrink tumors or slow cancer growth.

Guangzhou, Guangdong
NCT07208773Recruiting· Phase 1/Phase 2
Study of YL201 and Ivonescimab for advanced solid tumors

This trial tests a new drug combination (YL201 and Ivonescimab) for people with advanced solid tumors that have stopped responding to other treatments. The goal is to see if this combination can shrink tumors or slow their growth.

Guangzhou, Guangdong

Hear when a new Non Small Cell Lung Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.