Clin2
NCT07465263Possibly a fitRecruiting

Study of SYH2053 Injection for High Cholesterol in HeFH

Heterozygous Familial Hypercholesterolemia (HeFH)

Part of Genetic & congenital, Heart & circulation, Hormones & metabolism clinical trials.

This study tests a new injection called SYH2053 for people with HeFH, a genetic condition that causes very high cholesterol. It looks at whether the injection can safely lower LDL cholesterol when added to standard statin therapy.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
135 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have been diagnosed with heterozygous familial hypercholesterolemia (HeFH), a common genetic condition that causes high LDL cholesterol.
  • You are already taking a stable dose of a moderate or strong statin, with or without other cholesterol-lowering medicines.
  • You have been following a low-fat diet for at least 4 weeks before screening.
  • You do not have severe heart problems or a recent major heart event (like heart attack or stroke in the last 6 months).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07450378Not yet recruiting· Phase 3
Study of an investigational medicine for inherited high cholesterol

This study tests an investigational medicine called QLC7401 for people with a genetic condition called heterozygous familial hypercholesterolemia, which causes very high cholesterol. It aims to see if the new medicine can further lower bad cholesterol when added to your usual cholesterol treatments.

NCT07775339Not yet recruiting· Phase 3
Long-term safety and cholesterol lowering in children with familial hypercholesterolemia

This study is checking the long-term safety and how well a new injectable medicine (lerodalcibep) works to lower cholesterol in children and teens with familial hypercholesterolemia (an inherited condition causing very high cholesterol). It's for those who already finished an earlier study of this same medicine.

Delhi
NCT07421297Recruiting· Phase 3
Study of SYH2053 for high cholesterol in Chinese adults

This trial tests a new medication called SYH2053 for people with high cholesterol or mixed high cholesterol and triglycerides. If you have high LDL cholesterol and are not taking strong cholesterol medicines, you may be able to join. The study will see if this drug is safe and works well.

Beijing, Beijing Municipality
NCT07421284Not yet recruiting· Phase 3
New cholesterol-lowering medication for high cholesterol

This study tests a new medication called SYH2053 to see if it helps lower 'bad' cholesterol more effectively when added to your current statin therapy. It is for patients whose cholesterol is still not at their doctor's target level, and it aims to improve heart health.

Beijing, Beijing Municipality
NCT06568471Recruiting· Phase 3
Study of HST101 for high cholesterol in Chinese patients

This study tests a new injectable medication called HST101 for lowering cholesterol in people who are already taking cholesterol pills but still have high levels. It may help if you have heart disease or are at high risk.

Beijing, Beijing Municipality
NCT07489209Recruiting· Phase 2
Study of EDP167 for homozygous familial hypercholesterolemia

This trial tests a new drug, EDP167, for people with homozygous familial hypercholesterolemia (HoFH), a genetic condition that causes very high cholesterol. The goal is to see if EDP167 can lower 'bad' cholesterol (LDL-C).

Beijing

Hear when a new Heterozygous Familial Hypercholesterolemia (HeFH) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.