Studying nerve damage from chemotherapy in colorectal and lung cancer patients
Part of Brain & nervous system, Cancer, Digestive system, Lungs & breathing clinical trials.
This study looks for small molecules in the blood that might predict nerve damage caused by certain chemotherapies. If you have colorectal or lung cancer and are starting a specific chemo plan, this trial could help researchers understand why some people get nerve problems and others don't.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are being treated for colorectal cancer and will receive oxaliplatin chemo for at least 6 cycles
- Or you are being treated for lung cancer and will receive paclitaxel chemo for at least 4 cycles
- You do not have a neurodegenerative disease like Parkinson's or Alzheimer's
- You have not had a stroke in the past
- You do not already have significant nerve damage or pain
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at tiny particles in your blood to understand and potentially predict nerve damage caused by certain chemotherapy drugs. Researchers will monitor you before, during, and after your cancer treatment to see if these particles can help warn doctors about this common side effect.
This study looks at chemotherapy-related nerve damage (often felt as numbness, tingling, or pain) and why it happens and should matter. You may be eligible if you had a normal nerve check before chemotherapy started, or if your nerve symptoms are stable after finishing treatment.
This study looks at how chemotherapy that can affect nerves (“neurotoxic” chemo) changes nerve function over time. It may help researchers better measure nerve side effects and improve care for people who need these cancer treatments.
This study aims to find a blood test that can predict which patients will develop nerve pain or numbness (peripheral neuropathy) from certain chemotherapy drugs. You may be eligible if you are about to start treatment with paclitaxel, docetaxel, or oxaliplatin for at least 9 weeks.
This study looks at “TRP channels,” which are part of how nerves sense pain and temperature, to understand nerve pain (neuropathy) after chemotherapy. It may help improve how future treatments prevent or reduce nerve pain in people who have had certain chemotherapy drugs.
This study looks at how chemotherapy-related nerve damage affects daily activities like walking and standing. It includes people who currently have or have had nerve-damaging chemotherapy and are experiencing nerve pain or weakness.
Hear when a new Cancer, Lung trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.