Clin2
NCT07428681Possibly a fitNot yet recruiting

Lorazepam to prevent delirium in intensive care patients

Delirium Confusional State

Treatments studied

Part of Brain & nervous system clinical trials.

This study tests whether giving a low dose of lorazepam, a calming medicine, can help prevent delirium (confusion and agitation) in patients newly admitted to the intensive care unit (ICU). It may help patients recover more smoothly.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
260 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You were admitted to the ICU as an emergency or unplanned admission.
  • You have been in the ICU for less than 24 hours and in the hospital for less than 24 hours before that.
  • You have a certain risk score (called Anttila-Index) of 4 or higher, which means you are at higher risk for delirium.
  • You are not currently taking benzodiazepines (a class of sedative medicines) and do not need them for your condition.
  • You are not pregnant or breastfeeding, and you have no allergy to lorazepam.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07801092Recruiting
Sleep-promotion protocol to prevent delirium in intensive care patients

This trial tests a special sleep-promoting protocol (using eye masks, earplugs, and other measures) to help prevent delirium (sudden confusion) in intensive care patients. If you or a loved one are in the ICU, this treatment might help reduce confusion and improve recovery.

Çanakkale, Çanakkale
NCT03438526Recruiting· Phase 4
Melatonin treatment for low-activity delirium in ICU patients

This trial tests whether giving melatonin (or a placebo) can help adults in the intensive care unit who have a specific type of confusion called low-activity delirium. It aims to improve recovery by supporting sleep–wake regulation in the ICU.

Basel
NCT05713877Recruiting· Phase 2
Melatonin to treat confusion in ICU patients

This Phase 2 trial tests whether melatonin can reduce delirium, a sudden confusion that can happen in the ICU. If you qualify, you may be given melatonin to see if it improves alertness and comfort during an expected longer ICU stay.

Montreal, Quebec
NCT07265128Not yet recruiting· Phase 4
Sedation study to reduce confusion after heart valve surgery

This study compares two sedative medicines to see which one causes less confusion or delirium in older adults after heart valve surgery. Participants will be randomly assigned to receive one of the two medications during their surgery.

Seoul
NCT06509191Recruiting· Phase 2/Phase 3
Melatonin for preventing delirium in older hospital patients

This trial tests if giving melatonin (a natural sleep hormone) can help prevent delirium (sudden confusion) in older adults who are hospitalized. It may help you if you are 65 or older and admitted to the hospital for general medical care.

Muscat
NCT07407400Recruiting· Phase 4
Sleep medication to prevent confusion in older ICU patients

This study tests whether a sleep medication called lemborexant can help older patients in the ICU sleep better and prevent post-surgery confusion. It may be a good fit if you are over 65 and will be in the ICU for at least two days after surgery.

Bangkok

Hear when a new Delirium Confusional State trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.